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Education and lifestyle changes for the prevention of arrhyt
2019-06-18
Education and lifestyle changes for the prevention of arrhythmias are critical in BrS. Patients should be informed of the various modulators and precipitating factors that could cause malignant arrhythmias. A prominent S-wave in Lead I has recently been identified as an ECG marker of BrS [298A]. Fev
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Common and rare SCN A variants may contribute to AF
2019-06-18
Common and rare SCN10A variants may contribute to AF susceptibility [59,60]. SCN10A mutations (R14L and R1268Q) cause a loss of function of Nav1.5 current, which is expected to reduce excitability and lead to the development of the arrhythmogenic substrate responsible for BrS and AF. A common varian
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The imbalances in the current R D
2019-06-18
The imbalances in the current R&D system were the subject of the 2012 report of WHO\'s Consultative Expert Working Group on Research and Development (CEWG). The CEWG recommended a global binding agreement that provides a needs-driven and evidence-based framework for R&D, guided by the core principle
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br Methods br Results br Discussion br Conclusions
2019-06-17
Methods Results Discussion Conclusions Conflict of interest statement Introduction Pulmonary vein (PV) isolation using a conventional electrode catheter is an effective therapy for atrial fibrillation (AF) [1,2]. However, it requires a long procedure time and has occasionally been
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br Conflict of interest br Acknowledgments br Background
2019-06-17
Conflict of interest Acknowledgments Background of basic genetics The human genome contains approximately 3 billion nucleotide purchase SB273005 pairs contained in 23 chromosome pairs. Each chromosome contains hundreds to thousands of genes and the estimated 30,000 genes in the human genome
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Competing pressures for resources across sectors however mea
2019-06-15
Competing pressures for resources across sectors, however, mean that increasing the proportion of resources for health will be difficult. Efficiency gains in the health sector could help to make the case for more investment. Countries need to tackle major sources of inefficiency by doing more of the
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The patient had experienced cardiopulmonary arrest because o
2019-06-15
The patient had experienced cardiopulmonary arrest because of PEA and bradycardia at least twice while on oral treatment for variant angina, but neither ventricular fibrillation nor ventricular tachycardia was apparent. Spontaneous attacks occurred despite the use of an oral calcium blocker, and low
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VV optimization From the foregoing discussion
2019-06-15
VV optimization From the foregoing discussion, it is clear that AV delay programming to ensure ventricular preexcitation with optimal LV diastolic filling and systolic function is complex, and the optimal method that translates into improved patient outcomes is uncertain. These issues are even more
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br Methods The study protocol
2019-06-15
Methods The study protocol was approved by the ethics committee at Juntendo University Nerima Hospital. After informed consent was obtained, SBC measurement was performed using a blood sample from each participant. Plasma was separated from each sample immediately after collection by centrifugati
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Las l neas le comunican
2019-06-14
Las líneas le comunican nrf2 activator Felipe que él y sus marañones habían determinado salir De lo primero, denuncia la perversidad de la administración, encabezada por el virrey Cañete, “malo, lujurioso, ambicioso tirano”, quien “premió” a los hombres que combatieron la rebelión de Hernández Giró
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Studies of strategies to reduce greenhouse gas
2019-06-14
Studies of strategies to reduce greenhouse gas emissions and improve health in urban environments have shown the potential to achieve both environmental and health improvements. For example, modelled effects of low emission vehicles and increased walking and cycling in London and Delhi showed major
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br Methods br Results Among patients
2019-06-14
Methods Results Among 36 patients with 37 long RP tachycardias, there were 22 patients with 23 ATs (62%) and 14 patients with 14 non-ATs (10 uncommon AVNRTs and 4 PJRTs). Age, sex, and AV Wenckebach apexbio calculator length at baseline in the EP study were not significantly different between
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The indications for epicardial mapping are institutionally
2019-06-14
The indications for epicardial mapping are institutionally variable but typically performed after a failed endocardial approach or if the etiology of cardiomyopathy suggests a high likelihood of epicardial scar (Fig. 9). Studies of patients with NICM that underwent combined epicardial–endocardial ap
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Bepridil is a multichannel blocker suggesting that its pharm
2019-06-14
Bepridil is a multichannel blocker, suggesting that its pharmacological effects on cardiac myocytes are exerted by blocking Na [21], Ca [22], and K [23–25] channels. It has recently been reported that bepridil has a cardioprotective effect [26] by opening ATP-dependent K azidothymidine in mitochond
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This Ca overload activates the forward mode of the Na
2019-06-14
This Ca2+ overload activates the forward mode of the Na+/Ca+ exchanger (NCX), increases the transient inward current (Iti), and induces ventricular arrhythmias due to delayed after depolarizations (DADs). Subtypes of CPVT Several subtypes of CPVT have been reported (Table 1). The most common typ
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