• Introduction Multiple myeloma MM is the most frequent

  2019-06-19

  

  Introduction Multiple myeloma (MM) is the most frequent cancer to involve the skeleton with 80–90% of patients developing bone lesions during their disease course [1]. Myeloma bone lesions are purely osteolytic and are associated with severe and debilitating bone pain, pathologic fractures, hyperca

• En las reflexiones sobre la Isla del

  2019-06-18

  

  En las reflexiones sobre la “Isla del Encanto” de María Teresa Cortés en su aportación titulada “La configuración de la nación en la narrativa histórica puertorriqueña y el sistema de prácticas ecológicas, siglo ” retoma la labor informativa sobre Puerto Rico, hecha por el funcionario español de ori

• En este exordio de la carta hoy perdida que acompa

  2019-06-18

  

  En este exordio de la carta, hoy perdida, que acompañaba la obra de Pané, se expresan todas las dudas del Almirante que, a pesar de la hipótesis de la ausencia de idolatría entre los taínos (interpretación esencial para ofrecer una representación de los indígenas que justificara su dominio), se most

• Regarding the expression of NKp NCR

  2019-06-18

  

  Regarding the expression of NKp46/NCR1 (Fig. 1A and B), both increased and decreased expression are observed depending on patients. Interestingly, the expression of the inducible molecule NKp44/NCR2 is clearly induced in 3 patients (PT1, PT2 and PT5) both regarding the percentage and the MFI. In con

• The width of the QRS is often used to

  2019-06-18

  

  The width of the QRS is often used to ascertain the distance of the site of origin from the conduction system. In the absence of antiarrhythmics, which result in conduction slowing, VTs with narrow QRS are located closer to the purkinje system or septum. VTs originating from the epicardium have been

• Our investigation suggests that cardiac pacing improves not

  2019-06-18

  

  Our investigation suggests that cardiac pacing improves not only CSA but also OSA. The mechanism by which SDB is improved is unclear. CSA might be improved by reduction of periodic variations in heart rate, which are increased by leukotriene receptor antagonists and may result in part from changes i

• Currently we are unable to fully understand the diversity

  2019-06-18

  

  Currently, we are unable to fully understand the Donitriptan hydrochloride and distribution of the AT arising around the apex of the triangle of Koch. Koyama et al. closely studied the spatial and topographic variation in the distribution of this type of AT around the His-bundle [17]. As demonstrat

• Introduction Bone is a very dynamic tissue resulting from co

  2019-06-18

  

  Introduction Bone is a very dynamic tissue resulting from coordinated phases of formation and resorption called bone remodelling. Additional to its role in phosphocalcic homoeostasis, bone remodelling process is necessary for bone growth, for renewal of cellular and extracellular matrix components

• Further complicating matters is that although menopause

  2019-06-18

  

  Further complicating matters is that although menopause can increase serum BTMs, other normal physiological conditions, certain disease states, and drugs are also associated with elevated BTM concentrations [81–83]. Low body-mass index (BMI) is a risk factor for low bone density [84] and evidence ha

• This Ca overload activates the forward mode

  2019-06-18

  

  This Ca2+ overload activates the forward mode of the Na+/Ca+ exchanger (NCX), increases the transient inward current (Iti), and induces ventricular arrhythmias due to delayed after depolarizations (DADs). Subtypes of CPVT Several subtypes of CPVT have been reported (Table 1). The most common typ

• Education and lifestyle changes for the prevention of arrhyt

  2019-06-18

  

  Education and lifestyle changes for the prevention of arrhythmias are critical in BrS. Patients should be informed of the various modulators and precipitating factors that could cause malignant arrhythmias. A prominent S-wave in Lead I has recently been identified as an ECG marker of BrS [298A]. Fev

• Common and rare SCN A variants may contribute to AF

  2019-06-18

  

  Common and rare SCN10A variants may contribute to AF susceptibility [59,60]. SCN10A mutations (R14L and R1268Q) cause a loss of function of Nav1.5 current, which is expected to reduce excitability and lead to the development of the arrhythmogenic substrate responsible for BrS and AF. A common varian

• The imbalances in the current R D

  2019-06-18

  

  The imbalances in the current R&D system were the subject of the 2012 report of WHO\'s Consultative Expert Working Group on Research and Development (CEWG). The CEWG recommended a global binding agreement that provides a needs-driven and evidence-based framework for R&D, guided by the core principle

• br Methods br Results br Discussion br Conclusions

  2019-06-17

  

  Methods Results Discussion Conclusions Conflict of interest statement Introduction Pulmonary vein (PV) isolation using a conventional electrode catheter is an effective therapy for atrial fibrillation (AF) [1,2]. However, it requires a long procedure time and has occasionally been

• br Conflict of interest br Acknowledgments br Background

  2019-06-17

  

  Conflict of interest Acknowledgments Background of basic genetics The human genome contains approximately 3 billion nucleotide purchase SB273005 pairs contained in 23 chromosome pairs. Each chromosome contains hundreds to thousands of genes and the estimated 30,000 genes in the human genome

14564 records 943/971 page Previous Next First page 上5页 941942943944945 下5页 Last page