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The BDNF Val Met polymorphism is also associated with
2019-12-13
The BDNF Val66Met polymorphism is also associated with decreased dendritic arborization and impaired long-term potentiation [25]. This is particularly important for the hippocampus, and healthy individuals with a BDNF Val66Met allele have decreased hippocampal volumes [30]. Hippocampal atrophy is co
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br Methods br Results br Discussion Literature showed SN was
2019-12-13
Methods Results Discussion Literature showed SN was well studied for its antigastric ulcer, antiinflammatory, antihyperglycemic, and antihyperlipidemic properties. Although a recent publication reported that SN was found to exert its regulatory effect in animal cholesterol levels, the exact
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ClC is a member of the voltage
2019-12-13
ClC-3 is a member of the voltage-gated chloride channel superfamily and has many roles in cell proliferation, apoptosis, Cetylpyridinium Chloride progression and so on (Dai et al., 2005). A growing number of studies showed that ClC-3 encoded a volume-regulated Cl− channel (ICl,Vol) in heart, that c
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For this study we have used the
2019-12-13
For this study we have used the intermediate affinity mutant antigen HEL2× for immunization. However, we have observed a similar defect in the plasmablast differentiation of EBI2-deficient SWHEL Parathyroid hormone (1-34) (human) over a 10,000-fold affinity range by using WT HEL or the low-affinity
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RLS is a genetically complex disorder
2019-12-13
RLS is a genetically complex disorder in which genetic and environmental factors contribute to the phenotype (Trenkwalder, Allen, Högl, Paulus, & Winkelmann, 2016). This disease is highly familial and six genetic variants with single nucleotide polymorphisms have been identified by genome-wide assoc
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br Materials and methods br Statistical analysis All statist
2019-12-13
Materials and methods Statistical analysis All statistical analyses were performed using SPSS software version 20. Protein DMAT data of DNMTs and clinicopathological parameters were collected. Mann-Whitney U Test was used to assess the differential expression of nonparametric data of DNMTs pr
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br Experimental section br Notes br PDB ID
2019-12-13
Experimental section Notes PDB ID codes The atomic coordinates and structure factors of hDHODH in complex with compounds 4 (PDB id: 5MVC), 5 (PDB id: 5MVD) and 6 (PDB id: 5MUT) have been deposited in the RCSB Protein Data Bank. Acknowledgements This research was financially supported by
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In conclusion DDR ECD was shown to
2019-12-13
In conclusion, DDR1 ECD was shown to be sufficient for collagen mediated DDR1 oligomerization, and the oligomerized form binds to collagen with increased affinity. In full length receptors expressed on live cells, DDR1 oligomerization occurred on the cell surface in agreement with the role of DDR1 E
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Foretinib In this study it was noted that two
2019-12-13
In this study, it was noted that two out of five E. crassus CYPs (CYP5681A1 and CYP5682A1) had no intron, and 3 others had one intron at different positions (Fig. 3). Number and length of introns are varied in diverse species. For example, most hypotricha genes characterized so far lack introns (Pre
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br Neuroimaging Neuroimaging has not yet been
2019-12-13
Neuroimaging Neuroimaging has not yet been systematically reported in individuals with CDD, although case reports document normal gsk3beta anatomy or less often, show cortical atrophy or T2 fluid-attenuated inversion recovery hyperintensities in the white matter.15, 17, 18, 19, 48, 52, 54, 55, 6
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The identification of a functional leucine
2019-12-13
The identification of a functional leucine-rich NES mediating 8E7 nuclear export led us to analyze the interaction between 8E7 and CRM1 nuclear export receptor. HeLa cell lysates containing EGFP-8E7, EGFP–8cE7, EGFP-16E7–NES (as a positive control), or EGFP (as a negative control) were incubated wit
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JDTic 2HCl The current study had the following aims br
2019-12-13
The current study had the following 3 aims: Materials and methods Results Discussion Western Europe, USA/Canada, and Australia have traditionally been the areas in which cochlear JDTic 2HCl is most common [9], [10]; correspondingly, the most common and well-known validated tests and (re)h
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Nanocomposite films with a GNP DNA filler concentration
2019-12-12
Nanocomposite films with a GNP-DNA filler concentration of 20 wt%, 30 wt%, and 40 wt% were investigated by electrical impedance spectroscopy before and after UV-C irradiation (Fig. 2). EIS data were fitted to a RC-circuit model and surface resistivity values were calculated from the fitted resistanc
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For radiochemotherapy it is well known that mitotic
2019-12-12
For radiochemotherapy, it is well known that mitotic cell death and apoptosis present the major cell death modes. More recently, autophagy-dependent cell death has been described to occur upon radiochemotherapy (Daido et al., 2005, Song et al., 2017). This form of regulated cell death depends on com
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br Results br Discussion Adult hand foot and mouth disease
2019-12-12
Results Discussion Adult hand, foot and mouth disease gets no particular research interest because it has been seen as a sporadic mild viral infection that spontaneously resolved in a few days. However, evidence showed that adults may act as latent enterovirus reservoirs. A serum epidemiologic
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